CLINICAL & POPULATION HEALTH CORE
Progress towards meeting global public health tuberculosis (TB) targets for reductions in incidence, mortality and socioeconomic consequences have been slow, and in some cases reversed due to the recent COVID-19 pandemic.
Without reinvigorating TB clinical and population health research with an infusion of new investigators, novel perspectives, cutting-edge innovation, and rigorous implementation strategies we remain at risk of allowing the TB pandemic to continue unabated.
The goal of the Clinical Science and Population Health Core is to augment existing UCSF and UCB resources to accelerate clinical and population health research. We want to engage New Investigators with novel ideas, reduce regulatory barriers to research while maintaining scientific rigor, and increasing access to clinical and public health data and analytic resources so that more people can join the fight to end TB.
Specific Aims:
Provide consultation related to substantive TB clinical, translational, and population health methods
Curate and maintain a searchable data registry of clinical studies led by UCSF-UCB TB clinical researchers alongside publicly-available resources
Leverage a Global UC TRAC community advisory board to integrate community engagement into every aspect of our research program
Mentor new investigators (NIs) in the conduct of TB clinical research
Priya Shete, MD, MPH
Associate Professor, Medicine
UCSF
Patrick Phillips, PhD, MS, MA
Associate Professor, Medicine
UCSF
CORE DIRECTORS
Barbara Alonso
Clinical & Population Health Core Coordinator
Contact for any questions regarding the Core
Consultation Service for UCSF and UC Berkeley TB researchers
Consultation service is offered to UCSF and UC Berkeley TB researchers, as well as those new to TB, via the UCSF Clinical & Translational Science Institute (CTSI) across a broad range of research methods.
UC TB-CAB Call for Applications
The University of California at San Francisco and Berkeley Tuberculosis Research Advancement Center (UC TRAC) is launching a Tuberculosis Community Advisory Board (UC TB-CAB) in August 2023. UC TRAC is calling for applications from diverse individuals based in Uganda, Vietnam, and the San Francisco Bay Area to join its group of strong, research-literate community activists from TB-affected communities and networks in Africa, Asia, and North America. The UC TB-CAB is looking to establish representation that is diverse in geography, gender, experience and expertise.
Resources
SEATRAC Advanced TB Research Training
Courses presented during the University of Washington’s Advanced TB Research Training Course 9/18-22/23. Accessible for free through the course website.
Managed by NIH to facilitate meta-domain and domain specific TB data exploration and analysis. The TB Portals database contains linked clinical, bacterial genomic, and medical imaging data from TB patient cases.
The TB treatment individual patient data platform (TB-IPD) is a collaborative initiative to support the generation of reliable evidence on the treatment of TB to inform future TB treatment guidelines. It is supported by the WHO Global TB Programme and maintained by UCL.
Repository of data from TB treatment trials. There are currently data from 26 clinical trials from phase I through phase III, as well as a few latent TB trials.
Online platform by the WHO Global Tuberculosis Programme to track progress in the development of new treatment regiments, andvaccines as well as operational research projects designed to improve TB prevention, treatment, and care.